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KMID : 1022820120030020047
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Journal of Multiple Sclerosis and Neuroimmunology
2012 Volume.3 No. 2 p.47 ~ p.50
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Multiple Sclerosis and Monoclonal Antibody
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Park Su-Yeon
Sung Jung-Joon
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Abstract
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Multiple sclerosis is an inflammatory demyelinating disease of central nervous system caused by various autoimmune responses. Recent studies about pathophysiology of multiple sclerosis have led to development of various disease modifying drugs. Monoclonal antibodies are commonly used in treatment of autoimmune diseases and several cancers, but recently diverse clinical researches investigated about its effectiveness in multiple sclerosis. Monoclonal antibody belongs to targeted therapy with highly specific immune-modulatory property, so it may offer considerable effect over other conventional therapies for multiple sclerosis. Further studies are needed about therapeutic effect and safety of monoclonal antibodies in multiple sclerosis.
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KEYWORD
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Multiple sclerosis, Monoclonal antibodies, Targeted therapy
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